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Resume of NEM, MD, PhD
Consultant
EXPERTISE AND SERVICES
Biomedical Engineer, Cardiovascular Physiology Specialist, Biologist, Physiologist, Biophysicist, Defibrillation Expert, Biomedical Research Consultant, Fatigue Failure Analysis, Forensic Analysis, Patent Infringement, Engineering Consulting ServicesExpertise in biomedical engineering, cardiovascular physiology, research and development, medical education, and emergency cardiovascular care.
As an biomedical engineer, cardiovascular physiology specialist, this KKAI Associate's areas of expertise include motor evoked potentials, skeletal muscle ventricle physiology, cardiovascular physiology, mammalian physiology, human physiology, respiratory physiology, metabolic physiology, CPR, and cardiac defibrillation.
Additional experience and specialization includes veterinary medicine, measurement and control of blood pressure, implantable defibrillators, direct ventricular defibrillation, indirect ventricular defibrillation, transchest defibrillation, and cardiovascular studies.
Highly experienced in areas including electrocautery, defibrillation of the heart, ICDs, AEDs and transchest, engineering, medicine, biology, implantable sensors for closed-loop prosthetic systems, medical devices and instrumentation
PRINCIPAL INDUSTRIES SERVED
Biomedical, Cardiovascular Healthcare, Medical, Veterinary Medicine
EDUCATION
Ph.D., Physiology / Biophysics, Baylor College of Medicine, Houston, TX
M.D., Baylor College of Medicine, Houston, TX
B.S., Biology, Baylor University, Waco, TX
PROFESSIONAL EXPERIENCE
Consultant, Kevin Kennedy & Associates, Inc.
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Providing expertise in biomedical engineering, cardiovascular physiology, defibrillation, biomedical research, failure analysis, forensic investigation and analysis, patent infringement, and related expertise to a wide variety of clients.
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Professor of Basic Medical Sciences , major university
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Provided instruction, lectures and labs in areas including physiology, cardiovascular physiology, mammalian physiology, human physiology, respiratory physiology, metabolic physiology, and more.
Executive Director, William A. Hillenbrand Biomedical Engineering Center , Purdue University, West Lafayette, IN
Acting Director, William A. Hillenbrand Biomedical Engineering Center , Purdue University, West Lafayette, IN
Professor, Biomedical Engineering Center and School of Veterinary Medicine, Purdue University, West Lafayette, IN
Assistant Director, Division of Sponsored Programs, Purdue Research Foundation
Associate Director. William A. Hillenbrand Biomedical Engineering Center, Purdue University, West Lafayette, IN
Associate Professor, Biomedical Engineering Center and School of Veterinary Medicine, Purdue University, West Lafayette, IN
PROFESSIONAL REGISTRATION
Licensed physician in the state of Indiana
Licensed physician in the state of Ohio
Licensed physician in the state of Alaska
Licensed physician in the state of Texas
HONORS AND AWARDS
Alpha Epsilon Delta
American Institute for Medical and Biological Engineering (Fellow)
American Men and Women of Science
Beta Beta Beta
Society of Sigma Xi
Who's Who in America
PROFESSIONAL AFFILIATIONS
American Heart Association
American Physiological Society
Association for the Advancement of Medical Instrumentation
Indiana State Medical Association
Tippecanoe County Medical Society
PUBLICATIONS
Holds patents relative to apparatus and method for measurement and control of blood pressure, an electrode system and method for implantable defibrillators, and pressure mapping system with capacitive measuring pad.
Published in more than 150 refereed scientific journals on topics related to and including defibrillation without a-v block using capacitor discharge with added inductance, optimum duration of 60 hz current for direct ventricular defibrillation in dogs, minimum duration of capacitor discharge current for indirect ventricular defibrillation in dogs, the optimum current duration for capacitor discharge defibrillation of the canine ventricles, strength-duration curves for ventricular defibrillation, engineering and physiological considerations of direct capacitor-discharge ventricular defibrillation, ventricular defibrillation with single and multiple half sinusoidal pulses of current, defibrillation of dogs ventricles using single and multiple half-sinusoidal current pulses, total a-v block and asystole in a 94 kg pony successfully treated with external cardiac compression, nocturnal angina pectoris with disease of a single coronary artery, a megawatt defibrillator for trans-chest defibrillation of heavy subjects, ventricular defibrillation with single and twin pulses of half sinusoidal current, transchest electrical ventricular defibrillation of a 277 kg horse, threshold 60 hz current required for ventricular fibrillation in subjects of various body weights, cardiovascular studies on a dromedary camel, the electrocardiogram of a dromedary camel, ventricular defibrillation of a 341 kg horse using precordial electrodes, acute myocardial infarction, the electrical dose for ventricular defibrillation of large and small animals using precordial electrodes, the role of atrial impulses in the production of ventricular fibrillation, cardiac output in an anesthetized dromedary, experimental anesthetization of a dromedary camel, the electrical dose for ventricular defibrillation with electrodes applied directly to the heart, electrical threshold for defibrillation of canine ventricles following myocardial infarction, energy dosage for human trans-chest electrical ventricular defibrillation, low-energy electrical defibrillation of human hearts during cardiac surgery, electrode-subject impedance during transthoracic ventricular defibrillation, the audio-slide transcribed demonstration, trans-chest ventricular defibrillation of a subject weighing 102.5 kg, a-v block in a pony following jugular venous occlusion, trans-chest ventricular defibrillation of heavy subjects using trapezoidal current waveforms, a new electrical hazard associated with the electrocautery, the decrease in transthoracic impedance during successive ventricular defibrillation trials, electrical dose for defibrillation, the impedance of electrodes used for ventricular defibrillation, alteration of electrical defibrillation threshold by the cardiac glycoside ouabain, cardiac damage due to electric current and energy. light microscopic and ultrastructural observations of acute and delayed myocardial cellular injuries, damage produced in canine hearts following trans-chest dc electrical shock, increased efficacy of high energy defibrillation, clinical efficacy of a truncated exponential defibrillator, prediction of the impedance of the thorax to defibrillating current, energy dose for ventricular defibrillation of children, acute cardiac damage in dogs given multiple transthoracic shocks with a trapezoidal wave defibrillator, the thoracic windows for electrical ventricular defibrillation current, the effect of tilt on the strength-duration curve for trans-chest ventricular defibrillation, comparative efficacy of square and damped sine wave current for ventricular defibrillation, a very high energy defibrillator for research, bubble formation, arcing and waveform distortion produced in human blood by trapezoidal defibrillation current, efficacy of defibrillators for emergency medical services use, improvement of defibrillators for ems use: a problem in engineering and medicine, indirect mean blood pressure in the anesthetized pony, ventricular defibrillation, the electrical dose for direct ventricular defibrillation in man, effect of shock strength on survival of acute cardiac damage induced by open-chest defibrillation of dogs, cardiac damage produced by trans-chest damped sine wave shocks, sequential cardiac morphologic alterations induced by single transthoracic damped sinusoidal waveform defibrillator shocks, strength-duration curves for trapezoidal waveforms of various tilts for transchest defibrillation in animals, comparative efficacy of damped sine wave and square wave current for transchest ventricular defibrillation in animals, therapeutic indices for damped sinusoidal defibrillator shocks: quantitation of effective, toxic and lethal peak current doses, protection of ischemic myocardium by whole-body hypothermia after coronary artery occlusion in dogs, fundamental aspects of electrical ventricular defibrillation, electrocardiographic and serum enzymic alterations associated with cardiac alterations induced in dogs by single transthoracic damped sinusoidal defibrillator shocks of various strengths, elevation of ventricular defibrillation threshold in dogs by antiarrhythmic agents, automatic implantable defibrillation using a catheter-mounted electrode system, optimal spacing of right ventricular bipolar catheter electrodes for detecting cardiac pumping by an automatic implantable defibrillator, hemodynamic responses to two defibrillating trapezoidal waveforms, influence of adrenergic drugs upon vital organ perfusion during CPR, regional blood flow during cardiopulmonary resuscitation in dogs, the effect of newer antiarrhythmic drugs on defibrillation threshold, energy and current requirements for ventricular defibrillation using trapezoidal waves, therapeutic indices for transchest defibrillator shocks: effective, damaging and lethal electrical doses, dependence on defibrillation threshold upon extracellular/intracellular k\u+\d concentration, pervenous lead systems for the automatic implantable defibrillator (aid), an animal model for testing automatic defibrillators, bipolar catheter defibrillation in dogs using trapezoidal waveforms of various tilts, emergency ventricular defibrillation, recent advances in cardiopulmonary resuscitation, sequential ultrastructural alterations in ventricular myocardium of dogs given large single trans-thoracic sinusoidal waveform defibrillator shocks, emergency defibrillation, transchest defibrillation under conditions of hypothermia, cardiovascular alterations induced by chronic transvenous implantation of an automatic defibrillator electrode catheter in dogs, pulse transit time as an indicator of arterial blood pressure, in vitro resistivity of canine heart to defibrillator shocks, evaluation of an intracardiac catheter for use with an automatic implantable defibrillator, defibrillation effectiveness using disposable conductive gel pads, CPR with simultaneous compression and ventilation at high airway pressure in 4 animal models, recent developments in the treatment of sudden death syndrome, ultrastructural alterations in the fibrous sheath, endocardium, and myocardium of dogs shocked with chronically implanted automatic defibrillator leads, alterations induced by a single defibrillating shock applied through a chronically implanted catheter electrode, some research needs in defibrillation and CPR, ventricular fibrillation and defibrillation, cardiac damage in dogs with chronically implanted automatic defibrillator electrode catheters and given four episodes of multiple shocks, trans-chest defibrillation effectiveness and electrical impedance using disposable conductive pads, effects of myocardial infarction on catheter defibrillation threshold, impedance monitoring of equine intestinal motility, effect of whole-body hypothermia on myocardial blood flow and infarct salvage during coronary artery occlusion in dogs, increasing cardiac rate by measurement of right ventricular temperature, catheter electrode defibrillation in dogs, implantable defibrillator electrode systems, venous and arterial blood gases during and after cardiopulmonary resuscitation in dogs, optimization of epicardial electrode size and implant site for reduced sequential pulse defibrillation thresholds, manual versus mechanical cardiopulmonary resuscitation in an experimental canine model, sequential pulse defibrillation for implantable defibrillators, internal cardiac defibrillation in man: pronounced improvement with sequential pulse delivery to two different lead orientations, twenty-four hour survival in a canine model of cardiac arrest comparing three methods of manual cardiopulmonary resuscitation, the comparative pathology of open chest vs mechanical closed chest cardiopulmonary resuscitation in dogs, endotracheal versus intravenous epinephrine during electromechanical dissociation with CPR in dogs, influence of inspired oxygen concentration on acceleration atelectasis, induction and prevention of acceleration atelectasis, motor evoked potentials in dogs: effects of global ischemia on spinal cord and peripheral nerve signals, cardiopulmonary resuscitation with interposed abdominal compression, CPR-induced trauma: comparison of three manual methods in an experimental model, neurologic outcome following successful cardiopulmonary resuscitation in dogs, long-term survival with open-chest cardiac massage after ineffective closed-chest compression in a canine preparation, when to convert atrial fibrillation, comparison of the efficacy of defibrillation with the damped sine and constant-tilt current waveforms in the intact animal, sequential pulse defibrillation in man: comparison of thresholds in normal subjects and those with cardiac disease, internal ventricular defibrillation with sequential pulse countershock in pigs: comparison with single pulses and effects of pulse separation, comparison of mechanical techniques of cardiopulmonary resuscitation: survival and neurologic outcome in dogs, effects of naloxone on the adrenomedullary response during and after cardiopulmonary resuscitation in dogs, cerebrospinal fluid changes in experimental cardiac arrest (maximal stress), plasma catecholamine and serum cortisol responses to experimental cardiac arrest in dogs, aortic and right atrial systolic pressures during CPR: a potential indicator of the mechanism of blood flow, myocardial perfusion pressure: a predictor of 24 hour survival during prolonged cardiac arrest in dogs, a new implantable arterial pulse sensor for detection of ventricular fibrillation, paired comparisons of steroid-eluting and nonsteroid endocardial pacemaker leads in dogs: electrical performance and morphologic alterations, myocardial perfusion pressure: a predictor of 24-hour survival during prolonged cardiac arrest in dogs, changes in expired end-tidal carbon dioxide during cardiopulmonary resuscitation in dogs: a prognostic guide for resuscitation efforts, plasma catecholamines and resuscitation from prolonged cardiac arrest, existence of a strength-duration curve for spinal cord motor evoked potentials in cats, implanted pulse sensors for measuring pulse wave velocity, amplitude and latency characteristics of spinal cord motor evoked potentials in the rat, the use of electrically stimulated skeletal muscle to pump blood, the use of an electrically activated valve to control preload and provide maximal muscle blood flow with a skeletal-muscle ventricle, suprathreshold brain stimulation activates non-corticospinal motor evoked potentials in cats, amplitude and latency characteristics of spinal cord motor evoked potential in dogs, depletion of myocardial adenosine triphosphate during prolonged untreated ventricular fibrillation: effect on defibrillation success, comparison of usable skeletal muscle power from twitches and tetanic contractions of untrained muscles in dogs, lack of correlation between atpase staining and fatigue resistance of conditioned skeletal muscle, limitations of open-chest cardiac massage after prolonged untreated cardiac arrest in dogs, comparison of the damped sine wave to the capacitor discharge for low-energy electrical catheter ablation of the AV junction in dogs, pumping capabilities of the latissimus dorsi and rectus abdominis muscles wrapped around a valved pouch in a mock circulatory system, correlation of motor evoked potential response to ischemic spinal cord damage, the effect of skeletal muscle ventricle pouch pressure on muscle blood flow, tetrapolar electrode system for measuring physiologic events by impedance, comparison of the resistance to infection of intestinal submucosa arterial autografts versus polytetrafluoroethylene atrial protheses in a dog model, safety and effectiveness of new designs and materials of icd epicardial electrodes, preliminary results of deferoximine and l1 treatment of spinal cord ischemia, models for testing of transvenous atrial defibrillators: cholinergic enhancement techniques for maintaining stable atrial fibrillation, and more.
Author of books on the subjects of electrical defibrillation, research grants, defibrillation of the heart, ICDs, AEDs and transchest. Published author of book chapters on engineering, medicine, biology, implantable sensors for closed-loop prosthetic systems, medical devices and instrumentation.
Author of scientific abstracts published on topics including trans-chest defibrillation of heavy subjects, electrical dose for open-chest electrical ventricular defibrillation, electrode-subject impedance during trans-thoracic ventricular defibrillation, an energy dose for human ventricular defibrillation, increased electrical defibrillation threshold following myocardial infarction in canine ventricles, electrode-subject impedance during transthoracic ventricular defibrillation, quantitation of required energy for direct human cardiac defibrillation, electrical dosage for ventricular defibrillation, electrode-subject impedance during transthoracic ventricular defibrillation, electrode-subject impedance with successive defibrillation, evaluation of cardiac damage following electric shock with a defibrillator, defibrillation research, optimum location for precordial ventricular defibrillation electrodes, cardiac damage produced by high-energy, high-current defibrillation shocks, subject-dependent factors in ventricular defibrillation, whole-body hypothermia as therapy for acute myocardial infarction, histopathology and ultrastructure of myocardial injury caused by overdosed electrical defibrillation shocks, effect of morphine on protection of ischemic myocardium with hypothermia, indirect mean blood pressure in the equine, ultrastructural changes in myocardium of dogs following supra-threshold transchest defibrillating shock, trans-thoracic ventricular defibrillation: success and body weight, comparison of trapezoidal waveforms for bipolar catheter defibrillation: strength-duration curves for various tilts, acute cardiac damage in dogs given multiple transthoracic shocks with a trapezoidal wave defibrillator, effect of shock strength on survival and acute cardiac damage induced by open-chest defibrillation of dogs, the electrical dose for direct ventricular defibrillation, electrical dose for direct ventricular defibrillation in man, blood flow to vital organs during cardiopulmonary resuscitation, regional blood flow during cardiopulmonary resuscitation, a reliable detection system for an automatic implantable defibrillator, energy and current requirement for ventricular defibrillation in dogs and ponies using trapezoidal waves, effect of selenium-vitamin e on mortality and necrosis following very high current trans-chest, damped sine wave, defibrillator shocks, effects of myocardial infarction on defibrillation threshold using a pervenous electrode designed for use with an automatic implanted defibrillator, cardiopulmonary resuscitation with simultaneous compression and ventilation at high airway pressure in four animal models, effect of fibrillation duration on defibrillation threshold in dogs using a pervenous catheter-electrode designed for use with an automatic implantable defibrillator, ultrastructural alterations in the fibrous sheath, endocardium, and myocardium of dogs with chronically implanted automatic defibrillator electrode catheters and given single defibrillating shocks terminally, impedance mechanogram and electrogram for detection of ventricular fibrillation in dogs, an in vivo method to monitor mobility of the equine intestinal tract, defibrillation threshold rise in dogs after chronic implantation of an endocardial defibrillating lead, defibrillation threshold rise in dogs attributable to electrode dislodgement, ventricular defibrillation threshold in dogs using reciprocal pulses, ventricular defibrillation threshold - its relationship to the chance of defibrillating a subject, resistivity of blood to defibrillator-strength shocks, reduction of defibrillation threshold by using sequential pulses applied through multiple electrodes, resistivity of skeletal muscle, skin, fat and lung to defibrillator shocks, improved internal ventricular defibrillation with twin-pulse energy delivery, perivascular impedance sensors for in vivo chronic blood pressure measurement: detection systems for automatic defibrillators, cardiometers and blood pressure controller, exercise responsive pacing sing r.v. blood temperature, improved thresholds for internal cardiac defibrillation in man using sequential pulse countershock, energy reduction for implantable defibrillation using a sequential pulse method to decrease generator size and increase safety, increasing cardiac rate by measurement of right ventricular temperature, effect of diltiazem on brain blood flow following ischemia and reperfusion, effect of epicardial electrode size and implant location on defibrillation threshold using a new sequential pulse technique, improved detection for automatic implantable defibrillation, transvenous electrode system and sequential pulse stimulation for reduced implantable defibrillator thresholds, improved internal cardiac defibrillation in pigs with sequential pulse countershock energy delivery, improved internal cardiac defibrillation in man using sequential pulse countershock energy delivery, manual versus mechanical experimental CPR: a hemodynamic resuscitation and 25 hour survival comparison, resuscitation and twenty-four hour survival among three different modes of manual cardiopulmonary resuscitation, CPR -induced trauma among three different methods of basic cardiopulmonary resuscitation, comparison of CPR induced trauma among three methods of manual cardiopulmonary resuscitation in an animal model, twenty four hour survival in a canine model comparing three methods of manual cardiopulmonary resuscitation, possible role of a combined thoracic and vascular pump, automatic implantable defibrillators: two sequential pulses are as effective as three, sequential 2 and 3 pulse defibrillation for automatic internal defibrillation without thoracotomy, sequential pulse defibrillation in man: comparisons of thresholds in normals and those with cardiac disease, closed-chest trans-septal electrical ablation of bundle, comparative pathology of open-chest versus closed-chest cardiopulmonary resuscitation in dogs, effects of naloxone on the adrenomedullary response during and after cardiopulmonary resuscitation in dogs, three mechanical techniques of cardiopulmonary resuscitation in a canine model: 24 hour survival and neurological outcome, treatment of electro-mechanical dissociation with intracardiac epinephrine, sequential pulse defibrillation: comparisons between catheter to patch, three patch and four patch systems, defibrillation: comparison of damped sine and trapezoidal waveform effectiveness in the intact animal, plasma epinephrine and norepinephrine during CPR in dogs, electrical ablation of a-v junction in dogs, atp content of the left-ventricular endiomyocardium during prolonged ventricular fibrillation and cardiopulmonary resuscitation, components of the feline spinal cord motor evoked potential, strength-duration curves for complex spinal cord motor evoked potentials, electrical vs. magnetic brain stimulation to elicit motor evoked potentials, selection of motor evoked potential monitoring locations, monopolar vs. bipolar electrical brain stimulation in the genesis of feline motor evoked potentials, plasma catecholamine responses to prolonged cardiac arrest and attempted resuscitation, tissue stimulation using magnetic fields: current technology--uses and problems, low-energy electrical ablation of a-v junction using a single capacitor discharge, first report of ventricular ectopic beats in the dog produced by a magnetic stimulator, correlation of meps, sseps, regional blood flow, motor function and spinal cord histopathology in a canine model of spinal cord ischemia, evidence for non-corticospinal motor evoked potentials in cats using suprathreshold brain stimulation, a review of early studies of multiple pulse defibrillation, lack of correlation between atpase staining and fatigue resistance of conditioned skeletal muscle, comparison of usable skeletal muscle power from twitches and tetanic contractions of untrained muscles in dogs, biomedical engineering education for cost reduction of health care, catheter electrode evaluation for transvenous atrial defibrillation, effect of electrode size (length) on transvenous atrial defibrillation, experience with a single pass atrial defibrillation lead system, and more.
Please note that this is an abbreviated CV. A fully detailed unabridged CV is available under special circumstances.
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Kevin Kennedy & Associates, Inc.
Rapid Response Engineering® Solutions
3905 Vincennes Road, Suite 320
Indianapolis, Indiana 46268
(317) 536-7000 voice
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